Uses of Agludril 4mg

Agludril 4mg is used to treat type II diabetes with the main ingredient Glimepiride. So how to use Agludril 4mg to get the best effect?

Each Agludril tablet contains Glimepirid granule 170mg, corresponding to Glimepirid 4mg and other excipients such as: Lactose, Microcrystallin, Cellulose, Sodium starch Glycolat, Povidon, Magnesium stearate, Blue No.2 Aluminum lake, Ferric oxide. Agludril 4mg is used orally for the long-term treatment of non-insulin dependent diabetes mellitus (type II diabetes mellitus) in adult patients when blood glucose cannot be controlled with exercise. exercise, lose weight and eat. Agludril 4mg can be used in combination with Metlormin or with Glitazone or possibly with insulin.
Agludril 4mg should not be used in the following cases:
Patients with insulin-dependent diabetes mellitus- type I diabetes, diabetic ketoacidosis, pre-coma or coma due to diabetes. diabetes mellitus, acute illness or diabetic coma. All of these cases require insulin. Patients with severe kidney failure, severe liver failure Pregnant or trying to become pregnant, breast-feeding patients. Patients with hypersensitivity to Glimepiride, a history of allergy or hypersensitivity to sulfonamides, hypersensitivity to any ingredient in the formulation of Agludril 4mg.

Agludril 4mg drug combined with some of the following drugs may cause drug interactions such as:
Drugs that increase the serum glucose lowering effect of Agludril 4mg such as insulin, Chloramphenicol, Coumanrin derivatives, Disopyramid , Cyclophosphamide, Ifosfamide. MAO inhibitors. Non-steroidal anti-inflammatory drugs such as: salicylates, paraaminosalicylic acid, Phenylbutazone, Oxyphenbutazone, Azapropazon. Probenecids, Quinolones, Miconazole, beta-blockers, ACE inhibitors, male sex hormones and anabolic steroids. Drugs that increase blood glucose when combined with Agludril 4mg such as diuretics, thiazide diuretics, corticosteroids, catecholamines, diazoxid and other sympathomimetic drugs, glucagon drugs, high doses of nicotinic acid drugs, estrogens, oral contraceptives Contains Estrogen, Phenyroin, Phenothiazines, Thyroid Hormones, Rifampicin. All of the above classes of drugs can lead to hyperglycaemia and uncontrollable glucose, requiring an increased dose of Glimepiride in this case.

Agludril 4mg may cause some side effects as follows:
Common: Dizziness, dizziness, headache, nausea/vomiting, feeling of pain in the epigastric region, diarrhea, abdominal pain, confusion temporary visual disturbances. Uncommon: Allergies, pseudo-allergic reactions, redness, itching, urticaria. Rare: Increased liver enzymes, impaired liver function, jaundice, mild or severe thrombocytopenia, erythrocytosis, hemolytic anemia, leukopenia, agranulocytosis, allergic vasculitis, sensitive skin with light. Usually these side effects will subside and go away with treatment. In severe cases, the drug can be discontinued. Patients should inform their doctor, pharmacist of all the side effects they encounter during treatment with Agludril 4mg for timely handling.

Agludril 4mg is used as directed by your doctor or pharmacist. Usual dose of Agludril:
The starting dose is 1-2mg of Glimepiride once a day. If the patient is sensitive to the drug, a starting dose of 1mg Glimepiride/day can be used. Maintenance dose 1-4mg Glimepiride 1 time / day. If necessary, the dose can be increased after 1-2 weeks of treatment and should not exceed 2mg of Glimepiride at a time. The maximum dose is 8mg Glimepiride. The patient takes the drug once a day before or after the first meal. It is recommended to swallow the tablet whole without chewing with a glass of water about 350ml. Overdose can cause hypoglycemia causing headache, fatigue, tremors, sweating, anxiety, warm and cold skin, rapid heart rate, nervousness, increased blood pressure, irritability, .. These symptoms may appear 24 hours after taking the medicine.
Patients should inform the doctor, pharmacist of the symptoms encountered when overdose or severe cases need to be hospitalized immediately. Mild cases give glucose or white sugar 10-30g mixed in a glass of water and monitor blood glucose. Drink once every 15 minutes until blood glucose returns to normal limits.
In severe cases, the patient is comatose or unable to take the drug, it is necessary to inject 50ml of a 10% glucose solution rapidly into the vein per day. Thereafter, a slow intravenous infusion of 10-20% glucose solution is required and blood glucose is actively monitored for 24-48 hours. If taking too much, use gastric lavage and give activated charcoal.

Agludril 4mg drug needs to be taken correctly and with a reasonable diet and exercise. When there is a complication of low blood glucose, it should be treated promptly. Caution when using Agludril 4mg for patients with poor nutrition, liver failure, adrenal insufficiency, renal failure because these subjects are very prone to hypoglycemia. Patients should avoid stress, trauma, infection, and high fever because they may become uncontrollable in blood glucose while being treated with Glimepiride. In this case, insulin alone should be used instead of Glimepiride. When blood glucose has been controlled but after a period of time, blood glucose control may not be possible anymore, it is necessary to increase the dose or use in combination with Glitazone, Metformin or Glitazone. The use of Glimepiride may affect the ability to drive and use machines. In case the elderly, taking beta-blockers, sympathomimetic drugs, when hypoglycaemia neesy has low blood glucose, it should be handled promptly. Patients should be monitored blood glucose every 3-6 months.