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Adenosine 2′(3′)-monophosphate mixed isomers: sc-214496
Adenosine 2′(3′)-monophosphate mixed isomers (CAS 130-49-4)
CAS Number:
130-49-4
Purity:
≥97%
Molecular Weight:
347.22
Molecular Formula:
C10H14N5O7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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An adenosine derivative formed as a metabolite of adenosine-2′:3′-cyclic monophosphate. It is generated through the hydrolysis of 2′,3′-cAMP by a group of metal-dependent phosphodiesterases. Notably, 2′-AMP exhibits inhibitory effects on the proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells. This inhibition occurs via the activation of A2B receptors by both 2′-AMP and 3′-AMP.
References:
- A method for assessing efficiency of bacterial cell disruption and DNA release. | de Bruin, OM. and Birnboim, HC. 2016. BMC Microbiol. 16: 197. PMID: 27566276