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4-Piperidone Monohydrate Hydrochloride: sc-210144
4-Piperidone Monohydrate Hydrochloride (CAS 40064-34-4)
Alternate Names:
Ppd⋅HCl⋅H2O; 4,4-Piperidinediol hydrochloride, monohydrate
CAS Number:
40064-34-4
Molecular Weight:
153.61
Molecular Formula:
C5H9NO•H2O•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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4-Piperidone Monohydrate Hydrochloride finds utility in numerous scientific research endeavors encompassing organic synthesis, and biochemistry. Within organic synthesis, it acts as a crucial reagent, facilitating the synthesis of various organic compounds. In the realm of biochemistry, it plays a pivotal role in elucidating the structure and functionality of proteins and other vital biological molecules.
References:
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- Design, cytotoxic and fluorescent properties of novel N-phosphorylalkyl substituted E,E-3,5-bis(arylidene)piperid-4-ones. | Makarov, MV., et al. 2009. Eur J Med Chem. 44: 2135-44. PMID: 19046794
- Use of 4-piperidones in one-pot syntheses of novel, high-molecular-weight linear and virtually 100%-hyperbranched polymers. | Cruz, AR., et al. 2009. Chem Commun (Camb). 4408-10. PMID: 19597608
- CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones. | Lagisetty, P., et al. 2010. Bioorg Med Chem. 18: 6109-20. PMID: 20638855
- Anticancer activity of an imageable curcuminoid 1-[2-aminoethyl-(6-hydrazinopyridine-3-carbamidyl)-3,5-bis-(2-fluorobenzylidene)-4-piperidone (EFAH). | Lagisetty, P., et al. 2012. Chem Biol Drug Des. 79: 194-201. PMID: 22107757
- Ultrasound-promoted synthesis of novel bipodal and tripodalpiperidin-4-ones and silica chloride mediated conversion to its piperidin-4-ols: synthesis and structural confinements. | Rajesh, K., et al. 2012. Ultrason Sonochem. 19: 522-31. PMID: 22129974
- Design, synthesis and bioevaluation of novel N-substituted-3,5-bis(arylidene)-4-piperidone derivatives as cytotoxic and antitumor agents with fluorescent properties. | Sun, J., et al. 2014. Chem Biol Drug Des. 83: 392-400. PMID: 24148151
- Antibacterial activity of synthetic curcumin derivatives: 3,5-bis(benzylidene)-4-piperidone (EF24) and EF24-dimer linked via diethylenetriaminepentacetic acid (EF2DTPA). | Vilekar, P., et al. 2014. Appl Biochem Biotechnol. 172: 3363-73. PMID: 24532443
- Investigation of fatty acid conjugates of 3,5-bisarylmethylene-4-piperidone derivatives as antitumor agents and human topoisomerase-II alpha inhibitors. | Potter, E., et al. 2015. Bioorg Med Chem. 23: 411-21. PMID: 25577711
- Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts. | Roayapalley, PK., et al. 2021. Molecules. 26: PMID: 34885719
- Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. | Swain, RM., et al. 2022. Invest New Drugs. 40: 905-921. PMID: 35793039
- Synthesis and bio-properties of 4-piperidone containing compounds as curcumin mimics. | Girgis, AS., et al. 2022. RSC Adv. 12: 31102-31123. PMID: 36349009
- Cytotoxic evaluation of some 3,5-diarylidene-4-piperidones and various related quaternary ammonium compounds and analogs. | Dimmock, JR., et al. 1994. J Pharm Sci. 83: 1124-30. PMID: 7983596