Albuminuria (Grades) and Risk for CKD

Normal to mildly increased albuminuria:

 - Albumin excretion rate: < 30 mg/24 hours. 

 - Albumin-to-creatinine ratio < 30mg/g.

Moderately increased albuminuria (formerly Microalbuminuria):

 - Albumin excretion rate: 30-300 mg/24 hrs.

 - Albumin-to-creatinine ratio: 30-300 mg/g.

 - ↑ risk of progressive kidney disease & cardiovascular events.

Severely increased albuminuria (formerly Macroalbuminuria, overt proteinuria):

 - Albumin excretion rate: >300 mg/ 24 hrs.

 - Albumin-to-creatinine ratio: >300 mg/g.

 - Larger amounts of proteinuria associated with worse renal survival.

Nephrotic-range proteinuria:

 - Urine total protein: >3.5 g/day.

 - The presence of nephrotic range proteinuria with edema, hypoalbuminemia (<3.0 g/dL) & hyperlipidemia is defined as nephrotic syndrome.

 - Macroalbuminuria is a type of nephrotic range proteinuria



Satyendra Dhar, MD @DharSaty



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