Dulera (mometasone / formoterol) is a combination beta agonist and corticosteroid inhaler. It's used for maintenance treatment of asthma by helping to lowering inflammation in the lungs and keeping airways open. This inhaler is typically inhaled twice daily. When used regularly, Dulera (mometasone / formoterol) can lower the number and severity of asthma attacks. But it's not a rescue inhaler, so it won't help an asthma attack that has already started.
Maintenance treatment of asthma in adults and children age 5 years and older
Dulera (mometasone / formoterol) is a combination of two medications that work together to help treat asthma symptoms.
Mometasone is an inhaled corticosteroid. The exact way that it works to treat asthma isn't known. But it's thought to work directly in your lungs to lower inflammation and swelling, this making it easier for you to breathe.
Formoterol is a long-acting beta agonist. It works by relaxing the muscles in your lungs to open up your airways, making it easier to breathe.
Source: DailyMed
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Less common
headache
muscle aches
pain or tenderness around the eyes and cheekbones
stuffy or runny nose
tightness of the chest
troubled breathing
unusual tiredness or weakness
Rare
Sore mouth or tongue
white patches in the mouth or on the tongue
Incidence not known
Blindness
blurred vision
cough or hoarseness
creamy white, curd-like patches in the mouth or throat
darkening of the skin
decreased vision
dizziness
fainting
fever or chills
loss of appetite
lower back or side pain
mental depression
nausea or vomiting
pain when eating or swallowing
painful or difficult urination
skin rash
tearing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
Voice changes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Works well to prevent and lessen asthma symptoms
Combines two medications into a single inhaler for convenience
Can be used with a spacer if you have trouble getting the full dose with the inhaler
Doesn't replace your rescue inhaler
Need to inhale 2 puffs twice daily for it to work well
Can raise your risk for infections
The 50 mcg/5 mcg inhaler is blue, the 100 mcg/5 mcg inhaler is yellow, and the 200 mcg/5 mcg inhaler is purple. Make sure you know the dose you're supposed to be on so you know which color inhaler you should be using.
Store Dulera (mometasone / formoterol) at room temperature. If you have the 120-actuation inhaler, it can be stored in any position. If you have the 60-actuation inhaler, store it with the mouthpiece down or sideways.
Use Dulera (mometasone / formoterol) twice daily at the same times every day. This medication works best if it's taken regularly every day.
If you have sudden trouble breathing during an asthma attack, use your rescue inhaler. Dulera (mometasone / formoterol) won't treat an asthma attack as it's happening.
Call your provider if your breathing or peak flow meter results worsen. Also contact your provider if you're using your rescue inhaler more often than usual. These could be signs that your Dulera (mometasone / formoterol) dose is too low, or you need another long-acting medication to help manage your asthma.
Tips on how to use your Dulera (mometasone / formoterol) inhaler:
Carefully read the instructions or watch the instructional video on how to use your inhaler and ask your provider or pharmacist if you have any questions.
If you're using a new inhaler for the first time or if you haven't used it in more than 5 days, you'll need to prime your inhaler. To prime the inhaler, hold it upright and away from your face and spray 4 times. Shake the inhaler well between each test spray.
Shake your Dulera (mometasone / formoterol) inhaler well before every puff.
With your lips firmly around the Dulera (mometasone / formoterol) mouthpiece, take a slow and deep breath while pushing the button on the top of the canister to deliver the medication. Try to hold your breath for up to 10 seconds or for as long as you comfortably can. This allows time for the medication to reach deep into your lungs.
If you need to inhale more than one puff of Dulera (mometasone / formoterol), wait at least 30 seconds between inhalations.
Clean the mouthpiece of the Dulera (mometasone / formoterol) inhaler using clean, dry tissues at least once a week. Don't use water to clean any part of the inhaler.
Use the dose counter to track how many doses of Dulera (mometasone / formoterol) you have left so you know when to get a refill. When the display window shows you only have 20 inhalations left, you should get a refill. When the display window reads "0", throw your inhaler away, even if the canister isn't completely empty.
Dulera (mometasone / formoterol) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Risk factor: Not rinsing and spitting after using Dulera (mometasone / formoterol) | Weakened immune system from medical conditions or medications
Dulera (mometasone / formoterol) includes a steroid medication. When inhaled through the mouth, it can cause a fungal infection in your mouth and throat called thrush. To lower your risk for thrush, make sure to rinse your mouth with water and spit after each inhalation of Dulera (mometasone / formoterol). If you develop thrush, your provider might still ask you to continue Dulera (mometasone / formoterol). Sometimes, they might prescribe you a medication to treat this condition. Let your provider know if you notice symptoms of thrush, such as white patches in your mouth, cotton-like feeling in your mouth, pain while eating or swallowing, or loss of taste.
Inhaled medications, including Dulera (mometasone / formoterol), can sometimes cause a muscle spasm in your lungs (bronchospasm). This can lead to difficulty breathing, wheezing, cough, and chest discomfort. If you have a hard time breathing after inhaling Dulera (mometasone / formoterol), use your rescue inhaler and get medical attention right away.
Like all corticosteroid-containing medications, Dulera (mometasone / formoterol) can weaken your immune system and raise your risk for infections. And if you do get sick, this medication can make it harder for you to heal. Your risk for infections is higher if you're also taking other medications that also weaken your immune system. If you're currently being treated for a serious infection, such as tuberculosis, let your provider know. They might need to consider a different medication for your asthma. Let your provider know right away if you have symptoms of infections, such as fever, chills, body aches.
Risk factors: Using Dulera (mometasone / formoterol) for a long time | Using too much Dulera (mometasone / formoterol)
Using Dulera (mometasone / formoterol) for long periods of time or at a dose that's higher than recommended can cause more medication to be absorbed into the body. This can affect your body in different ways since the medication acts similar to cortisol (a natural stress hormone made by your body). You might experience symptoms of too much cortisol (called Cushing's disease), such as weight gain around your gut, puffiness of your face, and muscle weakness in the arms and legs.
On the other hand, Dulera (mometasone / formoterol) can also cause your body to make less natural cortisol. Symptoms of low cortisol include long-lasting fatigue, loss of appetite, nausea, and vomiting. If either problem is severe enough, you might need additional medical treatment.
Use Dulera (mometasone / formoterol) only as directed. Don't use more than the maximum number of inhalations each day. Use the lowest dose possible for the shortest amount of time.
It's possible for children to experience a delay in growth during treatment with Dulera (mometasone / formoterol). Children should use the lowest dose for the shortest amount of time needed. Your child's provider will check their growth regularly while they're receiving this medication. If you're concerned about how Dulera (mometasone / formoterol) might affect your child's growth, discuss with your child's provider to see if this medication is right for them.
Risk factors: History of glaucoma or cataracts
Though rare, people taking Dulera (mometasone / formoterol) have reported having higher pressure in the eyes, glaucoma, and cataracts. Talk to your eye provider before using Dulera (mometasone / formoterol) if you have glaucoma or cataracts because they might ask you to come in more often for eye exams. Also speak with them if you notice any changes to your vision while using the medication.
Risk factors: High blood pressure | Heart failure | Heart rate or rhythm problems | Taking more Dulera (mometasone / formoterol) than recommended
Dulera (mometasone / formoterol) can raise your blood pressure and heart rate. If you have high blood pressure or other heart problems, Dulera (mometasone / formoterol) can make it worse, especially if you take it more often than you're supposed to. Tell your provider if you develop dizziness, fatigue, tremor, nausea, rapid heartbeat, weakness, or difficulty sleeping while taking Dulera (mometasone / formoterol).
Ages 12 years and older: The typical dose is to inhale 2 puffs of either Dulera 100 mcg/5 mcg (mometasone/formoterol) or Dulera 200 mcg/5 mcg (mometasone/formoterol) by mouth twice daily.
Ages 5 up to 12 years: The typical dose is to inhale 2 puffs of Dulera 50 mcg/5 mcg (mometasone/formoterol) by mouth twice daily.
Your provider will pick a starting dose based on which other asthma medications you were previously taking before starting Dulera (mometasone / formoterol). After starting Dulera (mometasone / formoterol), your provider will adjust your dose based on how well the medication is controlling your asthma symptoms and if you're having side effects.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Treatment of sudden, severe asthma attack
Maintenance treatment of asthma in adults and children age 5 years and older
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American Lung Association. (2023). Measuring Your Peak Flow Rate.
Centers for Disease Control and Prevention. (2021). Candida infections of the mouth, throat, and esophagus.
Global Initiative for Asthma. (2022). Global strategy for asthma management and prevention, 2022.
National Institute of Diabetes and Digestive and Kidney Diseases. (2018). Symptoms & Causes of Adrenal Insufficiency & Addison's Disease
Organon LLC. (2023). DULERA- mometasone furoate and formoterol fumarate dihydrate aerosol [package insert]. DailyMed.
Organon. (n.d.). How to use Dulera.
You and Your Hormones. (2020). Cushing's disease.
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