Atropa belladonna, commonly known as belladonna or deadly nightshade, is a poisonous perennial herbaceous plant in the nightshade family Solanaceae, which also includes tomatoespotatoes, and eggplant (aubergine). It is native to EuropeNorth Africa, and Western Asia. Its distribution extends from Great Britain in the west to western Ukraine and the Iranian province of Gilan in the east. It is also naturalised or introduced in some parts of Canada and the United States.

The foliage and berries are extremely toxic when ingested, containing tropane alkaloids.[1][2] These toxins include atropinescopolamine and hyoscyamine, which cause delirium and hallucinations,[1][2][3] and are also used as pharmaceutical anticholinergics. These tropane alkaloids appear to be common in the family Solanaceae, as they are also present in plants of the genera BrugmansiaDatura and Hyoscyamus, of the same family but in different subfamilies and tribes than the nightshade.

Atropa belladonna has unpredictable effects.[1] The antidote for belladonna poisoning is physostigmine or pilocarpine, the same as for atropine.[4]

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