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Enfamil Enspire Optimum Baby Formula, with Immune-Supporting Lactoferrin, Our Closest Formula to Breast Milk, Brain Building DHA, Dual Prebiotics, Infant Formula Powder, Baby Milk, 20.5 Oz Tub

4.8 4.8 out of 5 stars 2,827 ratings
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$39.77 ($1.94 / Ounce)
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1.28 Pound (Pack of 1)
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Purchase options and add-ons

Brand Enfamil
Size 1.28 Pound (Pack of 1)
Item Weight 1.28 Pounds
Item Form Powder
Age Range (Description) Infant

About this item

  • OUR CLOSEST FORMULA TO BREAST MILK: Enspire Optimum is Enfamil’s closest formula to breast milk with lactoferrin, found in colostrum + breast milk, and Dual HMOs
  • PROTEIN YOUR BABY NEEDS: Enspire Optimum has lactoferrin; an important protein in breast milk + colostrum that aids in iron absorption and supports baby’s immune system
  • EXCLUSIVE HuMO6 IMMUNE BLEND: Formula designed from breast milk with key components, such as 2’-FL HMO, LNnT HMO, Vitamin C, Vitamin E, Zinc, and Selenium
  • PEACE OF MIND: Enspire Optimum has NO artificial growth hormones, NO artificial colors or flavors, and NON-GMO, designed for complete nutrition for babies through 12 months
  • TRUSTED BY PARENTS & PEDIATRICIANS*: Enfamil is the #1 Trusted Infant Formula Brand By Pediatricians* & Parents and the #1 Trusted Brand for Brain-Building & Immune Support.

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From the manufacturer

RTB
enspire nutrition facts 1
enspire nutrition facts 1
What is "clinically tested"? Clinically tested means the ingredients, such as DHA, prebiotics and MFGM components, have gone through evaluation in controlled clinical trials, ensuring their safety, effectiveness, and intended benefits. Enspire Optimum is proud to have clinically tested ingredients that you can trust.
What is lactoferrin? Lactoferrin is a key protein also found in breast milk and colostrum, and helps support baby’s immune system.
Closest to breast milk, how? Enspire Optimum is thoughtfully formulated after the gold standard of breast milk as the 1st leading formula with lactoferrin*, also found in breast milk and colostrum. It has an exclusive HuMO6 Premium Immune Blend, with 2 HMOs structurally identical to those in breast milk, and essential vitamins and minerals.
What is HuMO6? Enfamil Enspire Optimum has a premium blend of immune supporting ingredients, such as MHOs, vitamins and minerals. Our exclusive HuMO6 blend is designed to support tiny immune systems, because your baby's well-being is our top priority.
What are HMOs? 2'-FL HMO stands for 2'-Fucosyllactose and LNnT stands for Lacto-N-neotetraose. These two HMOs are a special kind of sugar also found in human breast milk. They're like a special treat for the good bacteria in a baby's tummy. They help the good bacteria grow, supporting a healthy tummy, immune system, and digestion!
enspire NP infant enspire ge old NP GE
Enfamil Enspire Optimum Enfamil NeuroPro Infant Enfamil Enspire Gentlease Enfamil NeuroPro Gentlease
See Details
Customer Reviews
4.8 out of 5 stars
2,827
4.8 out of 5 stars
6,766
4.7 out of 5 stars
1,794
4.8 out of 5 stars
5,417
Price $46.79 $34.87 — $37.96
Key Benefit Our Closest Formula to Breast Milk and has Brain Building DHA, HuMO6* Premium Immune Blend Brain Building DHA & MFGM Components‡, HuMO6* Immune Blend Our Closest Formula to Breast Milk, Relief from Fussiness, Crying, Gas & Spit-Up and has Brain Building DHA & MFGM Components‡ Relief from Fussiness, Crying, Gas & Spit-Up and has Brain Building DHA & MFGM Components‡, HuMO6* Gentle Immune Blend
Our Closest to Breast Milk ✓ ✓
Lactoferrin (A key protein found in breast milk & colostrum) ✓ ✓
Brain building DHA ✓ ✓ ✓ ✓
HuMO6 Immune Blend *2'-FL & LNnT HMO, Vit C & E, Selenium, Zinc *2-FL HMO, PDX, GOS, Vit C& E and Selenium *2'-FL HMO, Vitamin C & E, Selenium, partially hydrolyzed protein, and reduced lactose
For Fussiness, Gas, Crying & Spit-up ✓ ✓
MFGM Components‡ ✓ ✓ ✓ ✓

Product Description

Enfamil Enspire Infant Formula is an inspired way to nourish. Enspire has MFGM and Lactoferrin, two key components found in breast milk, making it our closest formula ever to breast milk. Enspire is a non-GMO† baby formula that is designed to provide complete nutrition for babies through 12 months. †Not made with genetically modified ingredients, but trace amounts of genetically engineered materials may be present in the product from manufacturing environments and process sources. **Enfamil is the #1 pediatrician recommended brand of Infant Formula - QuintilesIMS, using the ProVoice Survey fielded from October 1, 2016 to September 30, 2017. *Among those who have a preference; Based on the 2023 survey by AMC Global.

Product details

  • Is Discontinued By Manufacturer ‏ : ‎ No
  • Product Dimensions ‏ : ‎ 4.4 x 6.3 x 5.5 inches; 1.28 Pounds
  • Manufacturer recommended age ‏ : ‎ 0 - 1 years
  • Date First Available ‏ : ‎ January 21, 2016
  • Manufacturer ‏ : ‎ Mead Johnson Nutrition
  • ASIN ‏ : ‎ B01ASIEJPA
  • Country of Origin ‏ : ‎ USA
  • Customer Reviews:
    4.8 4.8 out of 5 stars 2,827 ratings

Important information

Safety Information

Do not use a microwave oven to warm formula. Serious burns may result. Failure to follow these instructions could result in severe harm. Once prepared, infant formula can spoil quickly. Either feed immediately or cover and store in refrigerator at 35–40°F (2–4°C) for no longer than 24 hours. Do not use prepared formula if it is unrefrigerated for more than a total of 2 hours. Do not freeze prepared formula. After feeding begins, use formula within 1 hour or discard.

Ingredients

NONFAT MILK, LACTOSE, VEGETABLE OIL (CONTAINS ONE OR MORE OF THE FOLLOWING: PALM OLEIN OIL, COCONUT OIL, SOY OIL, HIGH OLEIC SUNFLOWER OIL), WHEY PROTEIN CONCENTRATE, AND LESS THAN 2%: LACTO-N- NEOTETRAOSE", 2'-FUCOSYLLACTOSE", LACTOFERRIN, MORTIERELLA ALPINA OIL*, SCHIZOCHYTRIUM SP. OIL**, CALCIUM CARBONATE, CALCIUM PHOSPHATE, CUPRIC SULFATE, FERROUS SULFATE, MAGNESIUM OXIDE, MANGANESE SULFATE, POTASSIUM CHLORIDE, POTASSIUM CITRATE, POTASSIUM IODIDE, SODIUM CHLORIDE, SODIUM SELENITE, ZINC SULFATE, SOY LECITHIN, CHOLINE CHLORIDE, INOSITOL, ASCORBIC ACID, BIOTIN, CALCIUM PANTOTHENATE, FOLIC ACID, NIACINAMIDE, RIBOFLAVIN, THIAMIN HYDROCHLORIDE, VITAMIN B12, VITAMIN B6 HYDROCHLORIDE, VITAMIN D3, VITAMIN K₁, VITAMIN E ACETATE, VITAMIN A PALMITATE, TAURINE, L-CARNITINE. ||A SOURCE OF MFGM (MILK FAT GLOBULE MEMBRANE COMPOSED OF PROTEINS AND FATS) COMPONENTS ¶A SOURCE OF HMO (2'-FL & LNnT HUMAN MILK OLIGOSACCHARIDES) #A SOURCE OF ARACHIDONIC ACID (ARA) **A SOURCE OF DOCOSAHEXAENOIC ACID (DHA)

Legal Disclaimer

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

4.8 out of 5 stars
4.8 out of 5
2,827 global ratings
Failure to thrive..... now THRIVING because of this formula.
5 Stars
Failure to thrive..... now THRIVING because of this formula.
Ive been meaning to write this review for a while now.After a very difficult, but not very long, pregnancy, my son was born premature at 30 weeks at 3lbs 7 oz. After feeling betrayed by my body with being able to incubate him to term, I was ABSOLUTELY DETERMINED to nurse him. For the first three months, managed to nurse exclusively, but once he made it out of NICU, and I went back to back, nursing became more and more difficult. I couldn't keep up, and my son wasn't growing. The suggestion from the pediatrician came that it was time to start supplementing. One bottle became two, became three, and my supply dwindled more and more. Unfortunately, he still was not growing. The problem was he was spitting up about 75% of everything he would drink. We were having to limit him to 3-4oz bottles, and he was holding down maybe half of that. We changed his outfit 4+ times a day, and never were more than a few feet away from a burp cloth. His doctors though it was reflux, and gave him medication to take 4x a day, but it didn't help. He simply was not gaining weight like he should have been. Yellow, Purple, Nutramagin, the preemie formula, nothing was "sticking".Then we wandered through Publix, and saw this on the shelf. My husband and I debated back and forth, because it was almost twice the price of the others, but ultimately we decided it was worth a shot right?Took him home, gave him a bottle, and waited. No spit up. Fluke right?Next bottle.......... No spit up.Next....... bigger bottle. No spit up.Literally instantaneously, he was holding his bottles down. Every once in a while, after a 5-6oz bottle, he'd burp and spit up some, but generally speaking, he wasn't PUKING like he had been. And he started gaining weight. My 7 month old who had still been wearing 0-3 month old clothes, had a major growth spurt, and jumped to the top end of 3-6 month old clothes. He was doing amazing!!!So we said, great maybe he's outgrown this! And we switched back to the yellow one. His first bottle, he threw up the entire thing. His second bottle, he threw up the entire thing. He never got a third bottle. I still have a practically full can of yellow Enfamil sitting on top of my microwave because I can't bring myself to give it to him.We've been using this formula for 7 weeks now. He's gained TWO POUNDS, and is up to 6-9 month old clothes. It is so expensive, and WIC doesn't cover it, so we struggle to keep up with the cost, but to see my son not crying, or puking for the first time in his life, is a miracle.His 10 month old check up was last week. For the first time in his life, he is on the charts. He is 1% for his age now.Thank you Enfamil.
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Top reviews from the United States

Mady
5.0 out of 5 stars Amazing formula
Reviewed in the United States on April 22, 2024
Size: 1.28 Pound (Pack of 4)Verified Purchase
With my first lo I had a hell of a time finding formula for her. She started on neuro pro, then gentle ease and finally ended up with AR. She spit up alot with the first two options. Now with second lo I found the enspire one and geeze he eats it so well very little spit up and he still happily breast feeds and swaps to formula with my Avent bottles. Highly reccomend. My only wish is it came in the premixed bottles like the neuro pro options. It would make things much easier especially with the hospital reccomendation of heating the formula water to prevent contamination.
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Kymberlee Miller
5.0 out of 5 stars Great if in between Breast feedings
Reviewed in the United States on April 12, 2024
Size: 1.28 Pound (Pack of 1)Verified Purchase
I mostly breast feed and pump but sometimes I can't keep up with my little ones demands especially when he is cluster feeding. I was looking for a formula that would be as close to breat milk as possible that wouldnt give him alot of gas or hurt his tummy, that I could feed my baby between breast feedings or when we were on the go and this was the one he seems to like best for far. Doesn't seem to hurt his tummy and has alot of the nutritional benefits he needs that baby's get from natural breast milk!
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Intuitive Love
5.0 out of 5 stars Great for breastfed babies
Reviewed in the United States on April 10, 2024
Size: 1.28 Pound (Pack of 4)Verified Purchase
Love this formula I stopped breastfeeding and switched to this formula due to working a lot and my baby loves it and had no problems with the switch. When I first switched I didn’t see it in stores and it was very hard to find so I bought from Amazon once but now I’ve noticed target and Walmart are bringing it back. I can’t wait until my baby is off of formula however if your a breastfeeding mom or want to get something close try this.
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Best cake flour
5.0 out of 5 stars Really good
Reviewed in the United States on March 23, 2024
Size: 1.28 Pound (Pack of 4)Verified Purchase
I bought this for my niece and this is the only formula that doesn’t upset her stomach and technically Amazon is the only place you can find so thank you
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Christina
5.0 out of 5 stars The best IMO!
Reviewed in the United States on January 26, 2024
Size: 1.28 Pound (Pack of 4)Verified Purchase
I have used this formula to supplement with breast milk for about 6 months now and we love it, especially that it has lactoferrin which is probably which why it is expensive and at times hard to find. Nevertheless, this is a great formula that is easy on baby's tummy and made with high quality ingredients! I will not use anything else.
2 people found this helpful
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Jarret
5.0 out of 5 stars If you can afford it this is the winner.
Reviewed in the United States on May 10, 2022
Size: 1.28 Pound (Pack of 1)Verified Purchase
Let me start by saying this formula is likely not the "best tasting" one out there. "Best tasting" when it comes to food is often the worst when it comes to nutrition. If you're concerned about taste/smell this formula is probably not for you. I personally am un-bothered by the smell and only read the nutritional label when making my choice. If you're concerned about the quality of ingredients, don't want an obese child, and want to give your kid the best nutritional formula the US has to offer.... This product is for you.

Secondly, I highly recommend ordering the refill packs on Amazon. Get your initial plastic tub from the grocery store then refill it the $55 box from Amazon. It's cheaper and you don't have to worry about seals being broken.

This stuff is expensive.... But it helped develop my thriving 10-month-old who is talking, laughing, smiling, communicating, and hitting all of her physical milestones with ease. She was born 5 weeks early and we worried about her mental development. She was tiny and behind other babies at first in her milestones. Since my wife breastfed and could never keep up, this was initially recommended by our pediatrician to help supplement and eventually transition from breast milk. The lactoferrin and MFGM are the special ingredients along with lactose being it's only sweetener instead of corn syrup. The MFGM makes a big difference in mental development while the lactoferrin helps develop a healthy gut (which attributes to the loads of parents saying this is the only thing their little ones can keep down). These are the only two ingredients that set it apart from traditional formulas... and they truly make a world of difference. This stuff is great. If it is just a little too expensive check out Enfamil NeuroPro... Which is basically the same thing just minus the Lactoferrin (it still contains the brain developing MFGM). Hopefully next time our next child decides to stay in the belly full-term, the breastfeeding starts off on the right foot and continues through one year. If not, I won't think twice before using Enfamil Enspire again. It's truly a no-brainer and we are so grateful to Enfamil for developing this incredible formula.
29 people found this helpful
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