Cardura

Doxazosin is marketed under the name Cardura. Doxazosin is a member of the class of medications known as alpha blockers. The prostate and bladder neck's blood vessels and muscles are relaxed as a result of the action of alpha blockers, which facilitates urination. Male benign prostatic hyperplasia (BPH) is treated with Cardura. The prostate gland enlarges as a result of BPH. BPH symptoms include dribbling after urinating, difficulty urinating, a weak urine stream, and the urge to urinate even when your bladder is empty. Cardura can be used for additional conditions not covered in this medication guide.

Health Benefits

Male benign prostatic hyperplasia (BPH) is treated with Cardura. The prostate gland enlarges as a result of BPH. BPH symptoms include dribbling after urinating, difficulty urinating, a weak urine stream, and the urge to urinate even when your bladder is empty.

Cardura can be used for additional conditions not covered in this medication guide.

Risks and Side Effects

Cardura's typical side effects include:

• dizziness;
• lightheadedness;
• tiredness;
• back aches; or
• stomach ache.

If you experience any side effect that bothers you or does not go away, let your doctor know.

When you get up from a sitting or lying down position while taking Cardura, your blood pressure may drop suddenly. You might feel faint or woozy as a result of this. Take Cardura on an empty stomach at least 30 minutes before a meal to avoid this issue.

Cardura may make you think or act differently. If you drive or do anything else that calls for alertness, use caution.

Dosages

Cardura is typically started at a dose of 4 mg once daily. If your blood pressure cannot be controlled, your doctor may increase your dose to 8 mg once daily.

You can take Cardura with or without food.

Taking Cardura:

-If it is almost time for your next dose, skip the missed dose and take the medication as soon as you can. Never combine two doses into one.

-A maximum of 8 milligrams should be taken per day.

Storage

Store away from moisture, heat, and light at room temperature.

Interactions

Cardura and other drugs may interact. Inform your doctor about all prescription and non-prescription drugs you take. This includes medicines prescribed by other doctors as well as vitamins, minerals, and herbal products. Never begin taking a new medication without first consulting your physician.

Mechanism of Action

Cardura eases the muscles and blood vessels in the prostate and bladder neck, which facilitates urination.

Male benign prostatic hyperplasia (BPH) is treated with Cardura. The prostate gland enlarges as a result of BPH. BPH symptoms include dribbling after urinating, difficulty urinating, a weak urine stream, and the urge to urinate even when your bladder is empty.

There are additional uses for Cardura not covered by this medication guide.
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Pharmacokinetics

After oral administration, Cardura is quickly and completely absorbed. Within one to two hours (Tmax), the mean peak plasma concentration (Cmax) is attained. Cardura is 96% bound to albumin and other plasma proteins.

Cardura is primarily distributed in the extracellular fluid compartment and has a volume of distribution of about 17 L/kg.

Cardura is metabolized by CYP3A4 and primarily eliminated through the biliary system in the form of feces. In the urine, less than 10% of the dose is recovered as the original drug or its metabolites.

Cardura has a terminal elimination half-life of 20 to 26 hours.

Alternatives to Cardura

The treatment of BPH with medication is not limited to Cardura. Other drugs consist of:

- alpha blockers, including tamsulosin (Flomax), alfuzosin (Uroxatral), doxazosin (Cardura), prazosin (Minipress), and terazosin (Hytrin).

- Inhibitors of 5-alpha reductase, such as dutasteride (Avodart) and finasteride (Proscar).

- additional drugs, such as a 5-alpha reductase inhibitor and an alpha blocker taken together.