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The Malformed Eye

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Lee's Ophthalmic Histopathology

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Abstract

Malformations of the eye, orbit, and adnexa are encountered in three forms. The most common are of a relatively minor nature such as colobomata of the uveal tract and minor malformations of the retina and optic nerve head and do not require treatment. The next group are amenable to surgical intervention and excised tissue may be submitted to the laboratory for investigation. Lastly, there are those in which major or minor degrees of ocular malformation are associated with severe and often lethal systemic disorders (e.g., synophthalmia, anencephaly, and gross chromosomal abnormalities such as the trisomy D group); these abnormalities may be encountered at autopsy. To understand these developmental anomalies an understanding of normal development is required.

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  1. Department of Pathology, Queen Elizabeth University Hospital, Glasgow, UK

    Fiona Roberts

  2. Department of Pathology, Royal Infirmary of Edinburgh, Edinburgh, UK

    Chee Koon Thum

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Roberts, F., Thum, C.K. (2021). The Malformed Eye. In: Lee's Ophthalmic Histopathology. Springer, Cham. https://doi.org/10.1007/978-3-030-76525-5_8

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