D-dimer is formed by enzymatic degradation of cross-linked fibrin by plasmin and, therefore, serves as a direct marker of ongoing coagulation with fibrinolysis. The plasma level of D-dimer is used for the evaluation of the patient’s fibrinolytic status. D-dimer concentrations are a beneficial cardiac marker in the diagnosis of deep vein thrombosis and pulmonary embolism and are utilised as control and calibrator in various in vitro diagnostic testing kits. It can also be used as a coating antigen for ELISA or agglutination assays.
D-Dimer
Product Code : 00-AGN-CM-DMR-001
Specifications:
| Parameters | Acceptance Criteria |
|---|---|
| Physical Appearance | Clear Colourless Solution |
| Protein Concentration (OD at 280nm, Ext Coeff: 2.0) | ≥ 1.0 mg/ml |
| Purity by SDS PAGE | ≥ 90% (Band corresponding to Mol. Wt. of 190 kDa) |
| Storage buffer | Defibrinated CRP deficient plasma with Tris Saline containing 15mM NaN3, pH 8.0 ± 0.2 |
| Form | Tris-Saline with 0.09% NaN3, pH 7.4 ± 0.2 |
| Storage temperature | -20˚C |
| Shelf Life | 1 year |
| Anti HIV-1 & 2 (ELISA) | Negative |
| Anti HCV (ELISA) | Negative |
| HBsAg Antigen (ELISA) | Negative |
| Source of the product | Normal human plasma |
For research use or further manufacturing purposes only